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대한산부인과초음파학회지 제8권 제3호 2006년
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산전초음파로 진단된 신경모세포종 3예

연세대학교 의과대학 산부인과학교실
임승철,김인규,최현정,이현철,김세광,박용원


Prenatal diagnosis of neuroblastoma by ultrasonography : A report of three cases and review of literature

Seung Chul Lim, In Kyu Kim, Hyun Jung Choi, Hyun Chul Lee, Sei Kwang Kim, Yong Won Park,
Department of Obstetrics & Gynecology, Yonsei University College of Medicine, Seoul, Korea

Neuroblastoma is the most frequent malignant tumor in neonates. Prenatal sonography gives us great advantage in the diagnosis of congenital malformations and malignant tumors before birth. However, reported cases of prenatally diagnosed neuroblastoma are rare. The prenatal diagnosis of neuroblastoma may confer the advantages of early diagnosis of the tumor, as well as offering the potential for early therapy and improved survival because of the inverse relationship between patient age and survival. We experienced three cases of prenatally and postnatally diagnosed neuroblastoma in our institute. Two neuroblastomas were diagnosed at third trimester by prenatal sonography. In another case, the fetus was suspected to have a congenital cystic adenomatoid malformation of the lung prenatally, but finally diagnosed to have a neuroblastoma after birth. Adrenal masses were completely resected postnatally and pathologically confirmed to be neuroblastomas.

  • Key Word : Neuroblastoma, prenatal sonography, fetal MRI
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