Intramural pregnancy is among the rarest forms of ectopic pregnancy. It was first reported by Doederlein in 1913. The diagnostic criteria required for intramural pregnancy is that completely surrounded by uterine musculature and is separated
from the uterine cavity and fallopian tube. Because of the difficulty early diagnosis of intramural pregnancy, most cases were found after the onset of complications such as uterine rupture, shock and hemoperitoneum. Early detection of intramural
pregnancy with the use of transvaginal ultrasonogram is important, and CT or MRI is a very useful. We report a case of successful conservative chemotherapy for an intramural pregnancy with brief review of literatures.